Friday, November 29, 2019

Curriculum design and development

Introduction Curriculum development is a concept that has attracted a lot of discussion in respect to the way it can be appropriately defined. According UNESCO and IIEP (2006), there is no single definition of curriculum development. Most definitions focus on the syllabi and learning materials. The broader definitions consider that curriculum is concepts that include other factors within and outside the school systems.Advertising We will write a custom essay sample on Curriculum design and development specifically for you for only $16.05 $11/page Learn More Traditionally, curriculum was referred to as a group of courses that formed part of the school’s education program. This refers to the approved courses that have to be accomplished so that a student can be promoted to the next educational level. As the world continues to modernize its education systems, various definitions have been developed to explain the concept of curriculum development. Th erefore, curriculum can be defined as the organization of sequences of learning outcomes. The sequences are entrenched in the education system of a country, and are aimed at achieving quality education (UNESCO and IIEP, 2006). Schools and colleges have designed curriculums to develop the skills of students. This is aimed at achieving various professional requirements in the changing modern world. Therefore, the need for superior skills has contributed to the need for curriculum development in education systems worldwide.Curriculum development has been described as the process of planning aspects that are taught within an educational institution. Curriculum development is done to match the school courses and programs to the skills of students (Hedden, 2012). The aim is to develop a curriculum that provides educational sustainability in the long run; thereby achieving the goals of national development. Curriculum development focuses on major and minor topics and courses that contribut e to the students’ career development. Curriculum development refers to a wide range of discussions by different professions and organizations that make decisions concerning learning experiences. Such decisions need to be integrated in a national, regional, or local education system to ensure sustainable development (Braslavsky, n.d.). Curriculum development varies from country to country. The process can be controlled from a national level by the ministry of education or individual states as the case in some federal countries (Braslavsky, n.d.). Centralized countries usually apply a top-down approach in the development of curriculum. In this regard, the curriculum is presented to teachers who, once they adopt it, should teach the learners. Eventually, the curriculum is evaluated by all the parties concerned.Advertising Looking for essay on education? Let's see if we can help you! Get your first paper with 15% OFF Learn More According to Braslavsky (n.d.), the s ociety can control the process of drive curriculum development. This is referred to as the bottom-up curriculum development. The responses collected by teachers and other education officials are evaluated, and standards are set to develop the curriculum further. This system is mostly used by decentralized governments. Professional organizations that influence curriculum decisions The curriculum being developed should address the issues of relevance, sequence, and integration in a given community’s set up (Stabback, 2007). Therefore, the process can be influenced by various professional organizations that ensure that the curriculum meets the diverse, fundamental, national, economic, social, communal and personal objectives without any form discrimination. The organizations are usually composed of individuals from a common profession or specialization. Over the years, these organizations have actively participated in curriculum development to ensure sustainability of education institutions. This is done with the aim of expanding knowledge and skills to students (Hedden, 2012). Some organizations that influence curriculum development include: Accountants Association, Professional Engineering organizations, and the National Councils of Teachers. Name Links Purpose American Accounting Association-AAA http://commons.aaahq.org/files/0b14318188/Pathways_Commission_Final_Report_Complete.pdf The article aimed at integrating professionally oriented faculty into significant aspects of accounting education, programs, and research. National Council of Teachers of Mathematics https://www.nap.edu/read/5844/chapter/5 This article aimed at providing guidelines related to the teaching and learning of mathematics among students. This was meant to ensure that all students attain equal Standards-based mathematics education. Also, the teachers were assured of the growth opportunities in respect to their profession. Curriculum design and development The proce ss of curriculum development involves the design and development of integrated plans for learning, how to implement and evaluate the plans, and checking the outcome. Designing the curriculum involves critical analysis of the teaching and learning framework. The purpose of the design stage is to elucidate certain action plans for achieving the curriculum objectives. The process is done professionally and technically to avoid any overlap between the topics and the course. This results to the development of syllabuses that focus on certain areas or subjects.Advertising We will write a custom essay sample on Curriculum design and development specifically for you for only $16.05 $11/page Learn More The ultimate result of the process is usually a coherent flow of topics regarding the courses offered in education institutions. Curriculum development ensures that students receive integrated and coherent learning experience that contributes towards personal, aca demic, and professional learning experience (Stabback, 2007). Various steps are involved in the process of designing and developing curriculum. These steps are majorly followed when a new curriculum is required, or when curriculum reforms are indispensable. Curriculum development involves step-by-step contextual scan and research of relevant best practices. Consultations with various stakeholders followed by development of a curriculum framework are conducted before syllabuses are accepted. The accepted plans are then implemented, and proper monitoring is established to check whether everything concerning the curriculum is accurate. The review and amendment of the contents is necessary for the whole process to succeed. The process is systematic and has a clear focus on sub-systems to avoid disastrous outcomes and waste of resources. Having a systematic process in the development of the curriculum enables the elimination of any potential loop holes. At the same time, this articulates the international standards benchmarks (Stabback, 2007). The role of technology in curriculum development Technology plays a great role in curriculum development around the world. Over the years, technology has played a significant role in the world education curriculums. This has been viewed as the greatest improvement that curriculum development has ever witnessed. Computers have become a means of information delivery where web curricula and online modules are the common technologies that have positively transformed curriculum development (Ali, 2008; Scholl, 2001). Technology has supplemented the delivery of learning resources due to the growing number of publication and technological breakthroughs in research. Today, technological advancement offers standardized instructions and learning environment that is familiar and can be accessed from any destination (Ali, 2008).Advertising Looking for essay on education? Let's see if we can help you! Get your first paper with 15% OFF Learn More This has resulted in greater satisfaction amongst learners since they can share and access common resources. Technology has also reduced the time spent for curriculum development in a considerable manner as compared to the previous ways of curriculum development. Efficiency has also been achieved in the development of the curriculum as compared to traditional methods that required a lot of time (Scholl, 2001). School-wide Curriculum development initiative The Ministry of Education is charged with the responsibility of undertaking extensive curriculum research. This is aimed at collecting relevant responses about what should be changed, introduced, or done away with to improve the curriculum. This involves consultation from parents, teachers, education officials, administrators, and professional bodies among other stakeholders. The findings are then submitted to the special curriculum review committee that analyzes the process before agreeing on the areas and subjects that need to be addressed. Proper measures are established to ensure that the plans are implemented. In addition, proper checks are instituted to evaluate the progress of the plans (Braslavsky, n.d.). The close monitoring of the process facilitates further amendments to the curriculum. The major challenges experienced during curriculum development can be classified into three categories. This includes internal, social, and external challenges. With regard to internal challenges, the curriculum development experiences the challenge to conform with the requirements by the ministry. These requirements are important to the schools. The culture usually impacts the process, demanding for changes that recognize its values and norms. External forces may also prevail in curriculum development to ensure that the proposed curriculum addresses issues of international concern such as health, science, and human rights (Stabback, 2007). Conclusion Curriculum development is a complex process that requires commitm ent of the organization responsible and the various stakeholders. The process should be conducted with transparency and systematically so that the outcomes of the whole process become credible. The curriculum developed should embrace modern developments in technology. It should also adhere to the internationally accepted standard of an efficient curriculum. This ensures proper integration of the education system of the country. References Ali, I.I. (2008). Role technology educational research in curriculum development. Retrieved from https://www.aan.com/ Braslavsky, C.(n.d). The Curriculum. Retrieved from http://www.ibe.unesco.org/ Hedden, H.B.(2012). Professional and trade organizations. Retrieved from https://www.referenceforbusiness.com/encyclopedia/Per-Pro/Professional-and-Trade-Organizations.html Scholl, F.J.(2001). Case studies: Using Technology to Improve Curriculum Development: The Technology Source Archives The Technology Source Archives at the University of North Carolina . Web. Stabback, P.(2007). Guidelines for Constructing a Curriculum Framework for Basic Education.Presented at the Regional Workshop â€Å"What basic education for Africa?†Kigali, Rwanda – 25-28 September 2007 UNESCO-IBE. Retrieved from http://www.ibe.unesco.org/fileadmin/user_upload/COPs/News_documents/2007/0709Kigali/Curriculum_Framework_Guidelines.pdf UNESCO and IIEP.(2006). Guidebook for planning education in emergencies and reconstruction. Paris: International Institute for Educational Planning. This essay on Curriculum design and development was written and submitted by user Kinsey Q. to help you with your own studies. You are free to use it for research and reference purposes in order to write your own paper; however, you must cite it accordingly. You can donate your paper here.

Monday, November 25, 2019

ITALIAN IMMAGRANTS essays

ITALIAN IMMAGRANTS essays In the1920s the United States of America welcomed thousands of immigrants every day. They came to the United States looking for opportunity and a better life. From 1920 to1930, 4,652,115 people immigrated to the United States. 5550,460 of these were Italian. Italians like other immigrants faced many hardships when they arrived in the U.S. Most hardships were caused by racisms and naturism. Americans were not used to the immigrants and thought less of them. Italians were also blamed for many of the nations problems. The government raided many of the immigrants homes because the feared they were communist. The Sacco and Venzetti trial proves the blame the Americans put on immigrants. There was no substantial evidence in the case. They were still convicted because they were immigrants and there were prejudices against them and their beliefs. At first people didnt realize the art and culture that Italian immigrants brought with them. I think that if people werent scared of the new culture coming they would of learned from them. The Immigrants brought with them things that we now experience every day. Enrique Caruso was opera tenor who was one of the first musicians to commercialize Italian operas in America. The Italian Immigrants also brought their love of food with them. This leaves us today with many foods that are common to people who dont realize they didnt exist in this country until the Italian immigrants brought them. Food such as pizza, pasta, cheeses, and cold cuts are on Americans diets because of the immigrants. Paranoia struck the government in 1941. In the months immediately following Pearl Harbor. About 250 Italian Americans were interned. They were considered by the U.S. government to be security risks. By June 1942, the FBI interned 1,521 Italian Americans. They were sent to interment camps in Montana, Oklahoma and Tennessee. Most were released shortl ...

Thursday, November 21, 2019

Middle East Colonialism Essay Example | Topics and Well Written Essays - 1750 words

Middle East Colonialism - Essay Example The other transformations entailed the erosion of the economic and political independence and spirit of nationalism had finally begun suffocating the atmosphere. The Europeans had opted to protect the non-Muslims from the heinous acts of the Muslims in the empire. The empire was gradually losing its territories as calls for nationalism were ringing around Turkey and other Arab countries. As the empire was ageing the division between the powerful and less powerful continued to widen. Meanwhile, the colonial empires were rooting themselves by dividing colonies among the European powers. Apparently the colonial powers took advantage of the falling Ottoman Rule that had had enormous influence of the regions it had Balkanized. Cole (1999) illuminated that the driving factors for the distribution of territories among these powers were economic reasons, political reasons, strategic reasons, and partly nationalism. The economic reasons encompassed the deep need for the powers to find new mar ket for their produce as well as other resources that were deemed to exist in these acquired territories.   The strategic reasons entailed the need to occupy areas that were strategically located not only for economical benefit but to gain control of numerous states.   Besides the above illuminated reasons, the western powers were also driven by their deep need to adventure. The trend of annexation of territories by several powers influenced other western nations as well. Makdisi (2006) vindicated that earlier, between 1798 and 1801.

Wednesday, November 20, 2019

Critically discus Visit Scotland Organisation and its contribution to Essay

Critically discus Visit Scotland Organisation and its contribution to the development of Scottish tourism in the past ten years - Essay Example These organisations play a fundamental role in development of tourism products within different markets. This article presents an analysis of the national tourism agency for Scotland; VisitScotland. The article identifies the numerous approaches the organisation has pursued in development of tourism within the country, and the result of these strategies on the tourism industry in Scotland. The report provides several recommendations that could enhance the impact of the organisation on the tourism activities occurring within the country. Table of Contents Executive summary 1 Table of Contents 2 Introduction 3 Methodology 3 Background of Visit Scotland 3 Findings 4 Partnerships 4 Marketing 6 Provision of information 7 Quality and sustainability 7 Discussions 8 Recommendations 9 Conclusion 10 References 11 Introduction VisitScotland is the Scottish national tourism agency that undertakes the role of marketing the country as a tourist destination in the world. The organisation is a gover nment funded public body that plays a significant role in coordinating various stakeholders within the tourism industry, in Scotland. The organisation has continuously been actively involved in the development projects of many tourism-based investments within the country. ... These activities have provided significant impacts in the development of tourism activities within the country; consequently contributing to economic improvement through sustainable tourism activities (Yeoman, para 1). Methodology The research gathered in this report was taken from various literatures available online. Journal articles and books have also been utilised in gaining an objective perspective of the organisation. Background of Visit Scotland Visit Scotland is an executive public body in Scotland, which coordinates tourism activities in Scotland and acts as the national tourism agency. The organisation operates from head offices located in Edinburgh, Scotland as well as other locations across the country (VisitScotland, para 1). The organisation was established in 1969 as the Scottish Tourism Board, and has continued to undertake tourism related activities since inception. The organisation is charged with the responsibility of attracting visitors to the country; an ope ration it undertakes through advertising, promotional campaigns and many other approaches. The organisation works closely with VisitBritain, a similar organisation with similar tasks across the entire Britain. The organisation coordinates tourism-marketing activities within the country, and seeks to ensure sustainability of the tourism sector within the country (Yeoman, Galt, and Mcmahon-Beattie, 14). Findings The organisation has been fundamental in the sustainability of tourism activities within the country for many years. The presence of the organisations remains essential in the tourism activities undertaken through the country. The organisation has over

Monday, November 18, 2019

Privitization of CPB corporation for public broadcasting Essay

Privitization of CPB corporation for public broadcasting - Essay Example The value of science is being perverted and skepticism is more attractive to human mind (White, 1999). Feelings and emotions are prioritized and knowledge is considered irrelevant. Under fascism, some people even scholars consider theory is irrelevant but theory informs good practice and sustainable application (Tompkins, 2005). Theory represents foundation of good practices. Everyday, we are being bombarded with news of celebritization and marketization of goods and services. Too often, all the marketing and advertising serve only as an enticement to attract buyers and hence, the companies will earn higher profits as more and more people buy the products. So is the case of privatization. According to the market, privatization is the solution to public inefficiency but there is no apparent evidence that public sector is inefficient (Rosen, Boothe, Dhalby & Smith, 1999). Indeed, privatization has nothing to do with efficiency. On the contrary, privatization is to transfer public control and ownership of public resources to private sector (Shafritz & Russell, 2000; Guislain, 1997); to change the structure of the economy and the state; to internationalize the economy; to change the role of the state; and to reorganize a new system of a state and economy (Guislain, 1997). We are living under fascism with elite governance that rules by money, cost saving, and beyond democratic accountability (Shafritz & Russell, 2000). One that preaches anti corruption but foster competition while competition creates radical evil (Grenberg, 2005) and fraud, and kept alive by lies that are magnified by the media such as Thierer (1999) argued, in support to the privatization of Corporation of Public Broadcasting, â€Å"the public feel the CPB has performed, its mission is obsolete and redundant today. There now exists an endless variety of high-quality channels with entertainment, informational, and educational programs that do not rely on public funding to bring quality shows to

Saturday, November 16, 2019

Yosemite: Rights to its Legacy and Name

Yosemite: Rights to its Legacy and Name The planet Earth is an endless landscape of natural beauty, populated by people of many different cultures, races, and ethnic groups, each speaking various languages and practicing numerous religions. No matter ones religion, language, race, culture or ancestry, we are all one human race living on one planet. We have inherited the planet Earth from our ancestors; therefore it is an important part of our heritage, traditions, and cultures that make us who we are today. To appreciate our landscapes and the beauty of our planet, one must explore and appreciate its many wonders. Whether one lives in the suburbs or the city, it is most likely it is a short drive to see the beauty of the Earths landscapes that surround us. Aside, from natures scenery, there are many geographical settings that are a huge part of our heritage and civilization. Many of these landscapes are defined as cultural landscapes, geographic area where a historical event or places which show evidence that a person or a group of people have had a cultural impact(NPS). The Cultural Landscape Foundation defines these landscapes, as those sites that include historic sites, historic designed, historic vernacular and ethnographic landscapes, which reveal aspects of the countrys origins and relationships with the natural world(TCLF). Many countries have their own cultural landscapes that attract visitors from around the world, each offering its own unique aspects of the world and provides scenic, economic, ecological, social, recreational, and educational opportunities(TCLF). These cultural landscapes are pictures, similar to a family portrait, which one cherishes, protects and preserves for the future generation. These images tell a story that teaches us about our history, cultures, and traditions. One cultural landscape that is an important part of North American heritage is Yosemite National Park, which is situated in Californias central Sierra Nevada Mountain Range(NPS). This American antiquity is rich in ethnographic landscapes, which are natural resources that connect people with heritages, land settlements, sacred religious or ceremonial grounds, communities, and geological structures (TCLF). This federally designated park consists of 747,956 acres of wilderness, roughly the size of the state of Rhode Isla nd and is home to five of the worlds highest waterfalls and groves of Giant Sequoias (NPS). Yosemite is an archaeological wonder, which tells the story of Americas rich history long before Christopher Columbus came to America. The recorded history is that of the first settlers, the Ahwahneechee, the Native American people who lived on the land 8,000-10,000 years ago (Hamilton 12). According to US Parks website the native people of Yosemite had a rich heritage and culture of traditions, religion, songs and lived fairly peacefully in the Sierra Nevada foothill, until the arrival of Euro-American miners (US Parks). During the California Gold Rush (1848-1855), European- American settlers traveled to the Sierra Nevada to mine the land and seek their fortunes (Hamilton 12). Soon after their arrival, the local natives desperately tried to protect their homeland from the white settlers greed and the damage they are doing to their land. By 1849, thousands of miners had settled in the Sierra Nevada, forcing the natives in the valley region. In retaliation, the native attacked the pro spectors, leading to Mariposa War in December 1850 (Military Museum). In hopes of ending the conflict, James Savage, a businessman, and soldier of the Mexican-American Savage organized a militia of miners, who called themselves, the Mariposa Battalion, to violently force out the native populations and take over the land for the mining of gold (US Parks). The war ended in July 1851, with the signing of a peace treaty and also led to the discovery of the Yosemite Valley (Military Museum). The discovery spread across the world, drawing more settlers to the area. In the years that followed, given Yosemites uniqueness of natural landscapes and formations, the park attracted photographers and artist to create images of the majestic landscape, hence nicknaming it The Incomparable Valley (NPS). The valley also caught the attention of scientist, historians, and educators, who studied the landscape and the natural environment (NPS). However, over time the valley began to show signs of ecosystem damage, and for that reason, President Abraham Lincoln stepped in and created the Yosemite Grant Act, to protect Yosemite Valley and the Mariposa Grove(MilitaryMuseum.org). The act was signed in 1864, relinquishing the land to the State of California, making it the first land ser aside wholly for preservation, public use and our nations first state park(Military Museum.org). According to the National Park Service, an estimated 4 million people from around the world visit the park each year to enjoy the majestic beauty and history of yesterday(NPS). For the outdoor adventurer, the park offers camping, hiking and for the more adventurous, the thrill of rock climbing. Tourists can explore the historic mining sites, tour the primate lodging establishments, and villages of theAhwahneechee people. For educators, students and visitors who want to learn the history and explore the geological findings, the Yosemite Museum houses a magnificent collection of more than four million artifacts and over 10,000 books (NPS). In 1984, UNESCO, the United Nations Educational, Scientific and Cultural Organization, recognized Yosemite National Park, a natural and cultural heritage site which is valuable to humanity and the enjoyment of future generations and declared it a World Heritage Site (UNESCO). As a WHS, Yosemite is protected by the mission of the World Heritage Convention, an international partnership and legal presentation which safeguards cultural or natural places of outstanding universal value(UNESCO). To date, there are 1677 sites on the WSH list, and each year more are added or removed. Currently, 55 WHS, in threat of disappearance caused by natural deterioration, causes or disasters, land development, war, and or changes in ownership (UNESCO). In 2016, Yosemite National Park was is such danger and needed the assistance of UNESCO to protect it. For as Yosemites tourism grew, so did its need for a park management plan, contracts, and services from outside the US Parks Service and eventually, Yosemite was operating like Disney World, with themed hotels, concession stands, restaurants, and attractions. With that came big business and profits for those businesses not associated with the parks service and government of California. Even though Yosemite is a national landmark and protected by the state of California and the federal government, the Antiquities Act, the Parks Service, and UNESCO, the park is in peril. It is not in danger of environmental issues or changes due to human impact, the danger lurches from a big commercial enterprise. On March 1, 2016, US Park Service decided not to renew the contract of Delaware North, the hospitality company, who since 1993 operated the restaurants, hotels, shops, and other properties at Yosemite Park (Fuller). When the contract expired, the company took claim to the parks name and properties and refused to turn it over to the new hospitality company, Aramark (Hiltzik). Thus, forcing the National Park Service to either buy back the name or rename on the park, hotels, and attractions. According to an article in the Washington Post, journalist Sarah Kaplan stated that on the day Delaware Norths contract expired, two National Historic Landmark were renamed. The Ahwahnee Hotel became the Majestic Yosemite and Curry Village was renamed Half-Dome Village(Kaplan). All merchandise bearing the name Yosemite National Park was removed from gift shop(Kaplan). According to an article written by attorneys Klein Wilson, the lawsuit, has transformed the park [into a place where visitors feel a s if] greed has infiltrated [their world] (Klein Wilson). Changing the iconic names would take away everything we have come to know and cherish about the uniqueness, history, and heritage of the park. For the exclusive purpose of greed, a company is threatening to destroy the name of a national world heritage site, a global antiquity and a natural wonder of the world. A similar case of the rights to cultural property is the political and scientific legal battle over ÃÆ'-tzi the Iceman who was found near Hauslabjoch in the ÃÆ'-tzal Alps. According to the story, On September 19, 1991, two German hikers came across a well-preserved body of a man frozen in the ice (South Tyrol Museum). Since the discovery site was in close proximity to the Austrian-Italian border, neither government knew who had claimed to the 5,300-year-old corpse (South Tyrol Museum). After an investigation by Austrian scientists and archeologists, who believed him to be an ancient Austrian Trader, they nicknamed him ÃÆ'-tzi, after the region in which he was found. (South Tyrol Museum). However, after further research, it was discovered that the Iceman was actually an Ancient Italian Trader and the Italian government demanded the return of their cultural property. In 2001, based on this scientific evidence, Ortzi was returned to his homeland and now rests in the South Tyrol Museu m of Archaeology in Bolzano, Italy (South Tyrol Museum). In the case of Delaware North vs.Yosemite, the battle is over the legal rights to the trademarked name of a national icon. According to an article by Thomas Fuller, in the NY Times, the United States Trademark Act bars a trademark that falsely suggests a connection with a national symbol (Fuller). Fuller furthermore states, according to Sarah Maxwell, an official at the trademark office, the law bars trademarking national or state flags, but there was no explicit prohibition on the trademarking of other American icons(Fuller) According to Dan Jensen, a consultant to Delaware North, trademarking is a standard practice and Delaware North just wants its successor, Aramark, to pay for the full value of the intellectual property it is now managing(Hiltzik). Intellectual propertyrefers to creations of the mind, such as inventions; literary and artistic works; designs; and symbols, names and images used in commerce(WIPO)[A1]. In this lawsuit, the logos, images, and designs created by Delaware North are legally owned by them. Even though there are federal acts, and organizations like UNESCO to protect and preserve our national landmarks and cultural antiquities, there are loopholes that allow companies and groups to stake a claim to the properties. For example, many famous stadiums and arenas names are changed to sponsors name. To name a few, Riverfront Stadium, became Cinergy Field, San Diego Stadium was renamed Petco Park and legendary Candlestick Park is now known as ATT Park (Morran). Although stadiums arent national landmarks, they still hold the same historical significant for those who grown up going to those stadiums. For instance, baseball player, Willie Mays played his last game of his career at Shea Stadium, not Citi Field. [A2]Larry Bird played basketball at the renowned Boston Garden, not at TD Garden. [A3][A4][A5][A6] When did we become a country where marketing and profit were more important that [A7]holding on to our heritage? Our nations capital is named after our first [A8][A9]president George Washington. The Kennedy and Johnson Space Centers are named for presidents John F Kennedy and Lyndon Johnson, who supported the space program. Many buildings are dedicated to soldiers and others who have made the ultimate sacrifice for their country. If we allow corporations to change the names of these properties, we are permitting them to disrespect the memory of these great people and our history. We should never allow corporations for the mere purpose of marketing their products to change the names of historical sites and national landmarks. What if Taco Bell, bought the Statue of Liberty, would it be renamed The Taco Bell Lady? As more and more concessionaires, like Pepsi, Papa John, and [A10]Starbucks, are operating at historical landmarks, will the case of Delaware North set a precedent? Imagine Y ellowstone Park, being Starbucks Park or Niagara Falls, renamed Papa John Falls. This is what will happen if we continue to consent to commercialization of America.[A11][A12][A13] As an American citizen, one should stand up to the greed that threatens to destroy our heritage. We should look beyond the laws and statutes that allow companies to take away the names of cultural landscapes and properties that represents our nation and its people. It is our responsibility to protect and preserve this planet we inherited, and as in doing so, we are respecting and preserving the legacy of every World Heritage Site, so as to preserve the history for future generations. Works Cited   Ã‚   Beck, Warren A, and Ynez D Hasse. California and the Indian Wars: Mariposa Indian War, 1850-1851. California and the Indian Wars: Mariposa Indian War, 1850-1851, www.militarymuseum.org/Mariposa.html. Accessed 2 Mar. 2017. Fuller, Thomas. Bitter Contract Dispute Extends to Who Owns Yosemite Names. The New York Times, The New York Times, 1 Mar. 2016, www.nytimes.com/2016/03/02/us/bitter-contract-dispute-extends-to-who-owns-yosemite-national-park-names.html. Accessed 1 Mar. 2017. Hamilton, John. History. Yosemite National Park, Abdo Pub., Edina, MN, 2005, p. 12. Hiltzik, Michael. The Corporate Grab behind the Yosemite Park Trademark Clash. Los Angeles Times, www.latimes.com/business/hiltzik Accessed 15 Mar. 2017. Kaplan, Sarah. A Private Company Trademarked the Phrase Yosemite National Park. Should the U.S. Pay to Get It Back? The Washington Post, WP Company, 21 Mar. 2016, www.washingtonpost.com/news/morning-mix/wp/2016/03/21 Accessed 10 Mar. 2017. Klein Wilson. Defend Yourself against Copyright Infringement. Klein Wilson, 1 Mar. 2017, www.kleinandwilson.com/blog/2017/03/defend-yourself-against-copyright-infringement.shtml. Accessed 2 Mar. 2017 Morran, Chris. 20 Years Ago, Only 1 Baseball Stadium Had A Corporate Sponsor; Now All But 9 Do.Consumerist, 27 Sept. 2016, consumerist.com/2014/02/06/20-years-ago-only-1-baseball-stadium-had-a-corporate-sponsor-now-all-but-9-do/. Accessed 11 Mar. 2017. NPS. Defining Landscape Terminology / Cultural Landscape Guidelines. National Parks Service, U.S. Department of the Interior, www.nps.gov/tps/standards/four-treatments/landscape-guidelines/terminology.htm. Accessed 6 Mar. 2017. NPS. Rethinking the National Parks for the 21st Century. National Parks Service, U.S. Department of the Interior, www.nps.gov/policy/report.htm. Accessed 5 Mar. 2017. NPS. Yosemite National Park Celebrates 120th Birthday on October 1. National Parks Service, U.S. Department of the Interior, www.nps.gov/yose/learn/news/yose120.htm. Accessed 5 Mar. 2017.. South Tyrol Museum of Archaeology. The Discovery. South Tyrol Museum of Archaeology, www.iceman.it/en/the-discovery. Accessed 1 Mar. 2017. TCLF. About Cultural Landscapes. About Cultural Landscapes | The Cultural Landscape Foundation, The Cultural Landscape Foundation, 2001, tclf.org/places/about-cultural-landscapes. Accessed 6 Mar. 2017. UNESCO. UNESCO World Heritage Centre. http://whc.unesco.org/En/Culturallandscape, whc.unesco.org/. Accessed 2 Mar. 2017. US Parks Yosemite National Park History. Yosemite National Park History, National Parks Travel Guide Road Trip Planning, www.us-parks.com/yosemite-national-park/history.html. Accessed 5 Mar. 2017. WIPO. What is Intellectual Property? WIPO World Intellectual Property Organization. Accessed Web. 12 Mar. 2017. [A1]Inserted: IPO [A2]Inserted: , [A3]Deleted:, [A4]Deleted:ipo [A5]Deleted:s [A6]Deleted:, [A7]Inserted: ere [A8]Inserted: te [A9]Inserted: a [A10]Inserted: , [A11]Deleted:as [A12]Deleted:o [A13]Deleted:s

Wednesday, November 13, 2019

The Impact of Technology on a Home Schooled Education Essay -- essays

The Impact of Technology on a Home Schooled Education The field of technology is constantly improving, expanding, and changing. Over the past decade, Internet use and web-based communication have sky rocketed, enabling businesses, families, schools, and students to communicate more efficiently. An abundance of information is now available, literally, at the â€Å"click of a button.† This decade-long expansion of technology has had a remarkable impact on the effectiveness of home schooling, making sources available in seconds and instilling valuable life skills in each student that are vital for a successful future in this world of technological growth. The purpose of this research paper is to illustrate the positive impact of emerging technologies on home-schooled children, to demonstrate how technology is improving the effectiveness of these learning environments, and to display the augmentation of educational possibilities for students. The impact of the Internet and the great quantity of its use in public and home schools has grown tremendously over the past decade. Now, many children have the luxury of logging onto an instant messenger program to chat with friends instantaneously or sign into their personal email accounts to check new messages. Years ago, the idea of email was unheard of and unknown of to most. Suddenly it seemed that practically overnight, everyone had a personal email account. With this came the words â€Å"You’ve got mail,† and there began a new era. Email gave home-schooled students the advantage of being able to connect with others students easily. It connected students who live next door to each other to students who live in a complete different country. Email has facilitated the process of ... ...ademic Search/EBSCO database. Eichenlaub, N. (1999, November 28). E-Home Schooling: The Impact of the Internet on Home Schooling. Retrieved March 10 from the World Wide Web: http://www.slais.ubc.ca/people/students/student-projects/N_Eichenlaub/500-WWW/references.htm Strauss, Howard. (1999). The Future of the Web, Intelligent Devices, and Education. Educom Review, Volume 34 Number 4. Retrieved April 15, 2003 from the EDUCAUSE database on the World Wide Web: http://www.educause.edu/ir/library/html/erm9944.html Shemitz, J. (2002, December 29). Jon's Home school Page. Retrieved April 10, 2003 from the World Wide Web: http://www.midnightbeach.com/hs/ Rutkowski, Kathleen. (1998, May/June). Home school Pioneers on the Web. Voices of the Web. Retrieved April 9,. 2003 from the World Wide Web: http://www.infotoday.com/MMSchools/may98/voic0598.htm

Monday, November 11, 2019

Development of Anti-Idiotype Vaccine for Human Follicular Lymphoma

Non-Hodgkin’s lymphomas (NHL) constitute a heterogeneous group of malignancies whose incidence has significantly increased in recent decades. In the year 2000, more than 145,000 cases of NHL were diagnosed in developed countries, representing thus the sixth most common cancer occurring among men and the eighth among women. Low-grade B-cell NHLs, in particular, are incurable diseases characterized by relatively slow growth and excellent initial responsiveness to chemotherapy but also by continuous relapses. In particular, for patients with follicular lymphoma, median overall survival (7-10 years) has not improved over the past 30 years. Although in the vast majority of patients complete or partial remissions can be obtained with either single agents or combination chemotherapy, the clinical course is characterized by a high relapse rate. After relapse, both the response rate and relapse-free survival after subsequent salvage treatment regimens steadily decrease, resulting in a median survival of only 4-5 years after the first relapse. These clinical findings, coupled with the substantial toxicities of standard treatments, have stimulated the search for novel and more tumor-selective therapies.Follicular lymphoma is a clonal B cell malignancy that expresses a unique antigen that is formed by the immunoglobulin light and heavy chains that possess highly variable regions at their amino termini. These variable regions combine to form the antigen recognition site, which can itself be recognized as an antigen, termed the idiotype. The antigen-binding site is a structural feature of each immunoglobulin that distinguishes it from other immunoglobulins. The idiotype of a particular clonal B cell lymphoma represents a tumor-specific antigen. Idiotype is a target of interest in human lymphoma.Therapeutic vaccines targeting B cell lymphoma idiotype (Id) represent a promising immunotherapeutic approach for a better clinical control of these malignancies.Immunoglobulin (Ig) molecules are composed of heavy and light chains that possess highly variable regions at their amino termini. B-cell malignancies are clonal proliferations of Ig-producing cells. The idiotypic determinants of the surface Ig can thus serve as a tumor-specific marker for the malignant clone.Indeed, both protein- and dendritic cell-based vaccines that use the patient-specific Id have resulted in clinically significant tumor-specific cellular responses with very little toxicity. A broad use of Id-based vaccination for B cell lymphomas, however, is hampered by the fact that these approaches are patient-specific so that the vaccine must be individually produced for each patient. On these grounds, new strategies obviating the need to produce customized vaccines would further simplify clinical applications of idiotypic vaccines.Goals:Goal 1:Establishment of a large database including sequences of idiotypic VH and VL genes expressed by a variety of lymphoproliferative disorders, includ ing low grade B-NHL, autoimmunity-associated lymphoproliferations, and chronic lymphocytic leukemia. This will allow the identification of candidate Id proteins for â€Å"cross-reactive† immunotherapy.Goal 2:Pre-clinical characterization of the immunogenicity of selected natural Id proteins, with particular regard to their ability to induce immune responses against lymphoma cells expressing molecularly correlated Id proteins. The characterization will include the identification of B cell epitopes and HLA Class I-restricted cytotoxic T cell epitopes using innovative approaches and will allow the development of dedicated assays for immunomonitoring.Goal 3:Design and validation of optimized Id vaccine.Goal 4:Evaluation and validation of new adjuvants and innovative delivery systems for improved Id vaccine formulations and administration.Goal 5:â€Å"Clinical-grade† production and purification of optimized Id proteins for patient vaccination.IntroductionThere are approxima tely 65,000 new cases of non-Hodgkin’s lymphoma diagnosed each year in the US with a comparable number in Europe. Despite the use of aggressive chemotherapy and recent advances in therapy such as monoclonal antibodies (Rituxan, TM), the disease is almost invariably fatal. Follicular lymphoma (FL) patients, in particular, can have an indolent but ultimately fatal clinical course. The median relapse time for FL patients is three years, with 90% of patients dying of a tumor-related mortality within 7 years of the date of diagnosis.The clinical course is usually characterized by a series of remissions and relapses. Good response rates are seen with treatments such as chemotherapy, radiation, lymphocyte transplantation, and monoclonal antibodies. However, following initial response to treatment, the cancer invariably returns and the majority of patients relapse with resistance to all available therapy. Related B-cell derived neoplasms include multiple myeloma (approx. 15,000 cases /year in the US and chronic lymphocytic leukemia (approx. 10,000 cases/year in the US).Isolation of tumor-specific antigens (TSAs) has been a long sought-after goal for scientists involved in both basic and clinical research. Whereas tumor-associated antigens (TAAs) are localized on both normal and tumor cells, TSA are peculiar to tumor cells. This characteristic makes TSA a very desirable target for immune therapy strategies aiming to spare normal cells, or at least the indispensable ones.As regards effectors mechanisms, although some indirect evidence exists for participation of both natural killer (NK) cells (especially those activated by IL-2, known as lymphokine- activated killer, or LAK cells), and TNF-secreting macrophages in tumor immunity, most interest has been focused on the role of antigen-specific antibodies and T lymphocytes. This is particularly true among scientists developing anti-Id vaccines for human FL, even though no substantial agreement has yet been reached on which of the two main effectors pathways is most important.FL conforms to the general rule that tumors have several mechanisms to escape the attention of the immune system. The risks that Ig somatic hypermutations could result in aminoacid residue replacements leading to substantial changes within the fine immunogenic structure of the Id do not seem to be so relevant. Indeed, no such occurrence has been reported in any of the several dozen patients who have been immunized over the last decade. A much more relevant issue is the very limited ability of FL cells to present their own antigens.Although ontogenetically very close to normal mature B-lymphocytes, with respect to their normal counterparts FL cells are very poor as antigen presenting cells (APCs). This makes it rather difficult to evaluate any vaccine-induced, tumor-specific cytotoxicity even in vitro. On the other hand, no such problems exist for ELISA-based detection of the tumor-specific and vaccine-induced humoral respon se.The first study of anti-Id vaccinations in humans dates only from 1992. Until then, all the work had obviously been confined to animal models. However, the accumulation of experimental data has led to the development of several promising strategies that are currently being investigated in clinical trials. These include the utilization of the Id in the form of a soluble protein or as a DNA sequence, either used to pulse dendritic cells (DCs) or else to be administered in combination with immunologic adjuvants.Soluble protein Id vaccine production is based on a hybridoma technique, which in vitro allows production of exactly the same Ig as that present on the surface of the clonal B cells of FL, or in other words the tumor-specific Id. The suspension of single cells obtained from a biopsy specimen almost invariably contains a residual population of normal B-lymphocytes alongside the tumor cells. Screening of the hybridomas by means of Ig heavy chain CDR3 PCR identification is there fore required in order to make sure that the Ig of the selected hybridoma is truly identical to the tumor- associated one.31 Once the cultured hybridoma has yielded enough purified Id, the TSA needs to be made far more immunogenic than it is in its free form. For this purpose, it may either be conjugated with a highly immunogenic carrier such as keyhole limpet hemocyanin (KLH), or else used to pulse autologous DCs.The association of a soluble protein Id vaccine with immunologic adjuvants monocyte colony-stimulating-has also proved extremely important. Granulocyte factor (GM-CSF) currently seems to be the best such adjuvant both in animal models and humans, probably because of its capacity for local recruitment of DCs in vivo at the site of vaccine injections. This step would appear to be superfluous when autologous DCs are loaded with Id ex vivo and then re-injected into the patient.A completely different alternative approach involves administration of the patients’ Id-encodi ng DNA sequence. With the rise of molecular technology, such DNA vaccines are beginning to come into their own. For instance, exploitation of appropriate molecular vectors (ie containing both a leader and promoter sequence) for insertion of the nucleotide sequences responsible for biosynthesis of both the Ig heavy and light chains variable regions is now relatively easy.Between the heavy- and light-chains variable regions sequences, an intertwined linker peptide must also be inserted to allow the ultimate Id-containing molecule (scFv) to fold properly. Furthermore, the vaccine can be further strengthened by adding other DNA sequences encoding for immunologic adjuvants or powerful immunogens to the vector. Finally, intramuscular injections allow progressive release of the Id following synthesis by muscular cells. In addition, this administration route seems to be associated with prolonged conservation of the genetic information within the cells without any apparent signs of integrati on into their genome.Experimental DesignGoal 1:Establishment of a large database including sequences of idiotypic VH and VL genes expressed by a variety of lymphoproliferative disorders, including low grade B-NHL, autoimmunity-associated lymphoproliferations, and chronic lymphocytic leukemia. This will allow the identification of candidate Id proteins for â€Å"cross-reactive† immunotherapy.In establishing a database, there will be steps to follow in order to support the evidences claimed.I. Finding the cases and the occurrence of VH and VL in lymphoproliferative disorders in different hospitals and institutions that could provide valuable information for the said disorders. The facts and information should have the confirmed consent of the persons involved.II. Subjecting the cases to thorough analysis to provide the essential information needed in documenting the cases.III.   Testing the subject under the identification of Id proteins.IV. Organizing the information and est ablishing the database.Methods:Establishing a database to easily organize information and data needed in making the information available readily whenever they will analyze situation in which there is a suspected occurrence of lymphoproliferative disorder. By providing the information needed, they could develop system that would make things easier for them to do actions required in addressing such situation.Primary step is consolidating all the available facts and information provided that they have the consent from the owner of the information. By having the desired facts available for the reorganization of it, they could classify it according to the general category they want to use in creating their database. It could be based on severity of the case or could be base on gender or any factor that could greatly affect the situation.Then, by gathering the information they needed, the analysis of the data should be carefully done for them to eliminate excess and negligible data for a n easier organization of the structure of their available resources. By implicating the main thrust of the database to the core concept of having advance cases of NHL, the higher chance they could get the information and the data based on the clinical findings of actual patients and people who suffered from that.By simply opening the way of introducing different vaccines in addressing the situation, they could develop a system of transferring and managing information that could make things easier especially in developing new technology and medicinal advancement in creating a better and more effective ways of treating such disease. By making the information more manageable, they could likely innovate an advance communication that would lead them in establishing better information and data management for the use of the development of vaccines and cures.Since they have the information but they should examine carefully every bit of information that will be a part of their set of data an d facts. By looking closely to the subjects result and the specification of the action done, the development of such process in introducing a new finding on the matter should be considered. Since the goal is to establish a database that will focus on the information that could provide the facts needed on the cases diagnosed with a NHL, it is important to screen the cases as important and not negligible for them to be able to use it as a case.At the end of the process, they would go back to their primary goal and that is to establish a functional database that the core information and the key factors are integrated in a way that it would make the processing of facts and vital data would be efficient and effectively handled.Also, it will introduce technology that would compensate the fast rising of development in technological advancement even in the field of medicine. Because there are ready to use valuable information for them to handle and initialize their desired action, they woul d be able to commend the different opportunities in which they could get specimens and studied it for future discoveries and researches.In all, by their incorporation of the cases of NHL and their desired goal of making the information available for them to be able to easily study and review the situations and cases they previously have for them to execute and evaluate the validity of the existing tests in the current occurrence of the disease in the real place.Goal 2:Pre-clinical characterization of the immunogenicity of selected natural Id proteins, with particular regard to their ability to induce immune responses against lymphoma cells expressing molecularly correlated Id proteins. The characterization will include the identification of B cell epitopes and HLA Class I-restricted cytotoxic T cell epitopes using innovative approaches and will allow the development of dedicated assays for immunomonitoring.In dealing with the pre-classification of the immunogenicity of selected natu ral Id proteins, the processes involved are:I.   Accumulating soluble proteins to be tested.II. Testing them with hybridoma essential in testing the equivalence of the tumor inducing material that leads to development of the tumor.III.   Inducing the effect of the proteins and identifying its effect on B cells.IV. Using advance technique in analyzing the result and implicating with the use of the modern testing equipment and processes.Accumulation:Testing the proteins for it to be classified will be the first step. From the patients who are suffering from FL, different samples will be getting for the medical technology to be applied. Then by cultivating natural proteins, they will use it to further test the capacity of the natural cell in penetrating and deeply interacting with other Id proteins in the development of resistance to such substance.By eradicating some external factors such as the presence of other organisms, they could screen the protein level for them to be able t o produce and test the Id proteins by exposing it to toxoids that could develop resistance on the desired solution. Then, the Id proteins gathered will be stored for further testing.Testing:Then, preparation of the Id protein to be tested will be carefully done in a controlled environment. Since the tumor development can not be detected by the immune system, the development of inducing material will be necessary for them to penetrate the basic defenses of the tumor.By exposing it to NKL, tumor will exhibit a different behavior but will not be extinguished. Since B cells epitope derived multiply myeloma that had been the major cause of the return of the behavior of the tumor cells, the gradual exposing it to be classified by soluble Id proteins will be dedicated.The allowance of certain percent productivity will be the basic goal of the clinical testing for them to be able to derive the pre-classification scheme that will determine substances that induce immunity on certain level wit h the use of soluble and Id protein present in the environment.Effect and its IdentificationAfter the testing had been carefully done, they will examine its effect on various elemental positions by trying the substance on the possible outcome. Then, FL cells will be isolated then proteins will be added to see the effect on the neoplasms produced by B-cells. Since the outcome would produce certain behavior that will exhibit a different expected one, the process will be repeatedly associated with soluble proteins to target the development of TSA since it target tumor cells.Analyzing the ResultThen, the result will be analyzed in a way that it consistently produces same output. Then after looking closely and making sure that no other substance induced the effect, the validity of the result will be the next concern in analyzing the data. For it to be valuabe, the result should consist the scientific analysis of the vaccine to be introduced for them to be able to adopt a real one.Goal 3: Design and validation of optimized Id vaccine.Since the protein had been introduced in TSA that would target tumor cells, it is important to develop the next stage wherein it will pay attention to that. Tumor cells, after being extinguished by some other methods, always come back and provide a worse situation that before. It is a common problem of the development of cure because as soon as they introduce stronger antigens and antibiotics, the cells develop stronger immunity to them, making them more powerful and gave them the power to come back and come back whenever they are defeated.The result of the previous testing of the material will be used as the raw data in determining the precise development of the vaccine needed for the tumor cells. Toxoids produced by microorganisms will be introduced to the tumor cells for them to create an astounding reaction with the cells to help the antigens produce a better shield to the tumor cells.They would also address the production of its own immunity by targeting the B cells epitopes produced by the tumor cells for them to be able to weaken the effect of the tumor cells in the body. By simply having the same effect on the cells, they would establish the immunity desired.In addition, since soluble proteins produces amino acid residue, the effect of it to the development of various outgoing tumor cells will be beneficial in the sense that it would catch up the screening proves by a hard core stimulation of heavy chain CDR3 PCR. Then, the use of material that would likely predict the behavior will also introduce for the existing antigen to determine it.Goal 4:Evaluation and validation of new adjuvants and innovative delivery systems for improved Id vaccine formulations and administration.After having the result of the vaccine being tested hand-on on the tumor cells, the activation of the production of antigens will be manipulated for those to be able manage the outcome of the result. By having the systematic chain of micr o toxoids that will enter the entire system of the body, they would likely produce different kinds of reactions that would benefit the production of self stimulating antigens.By exposing it to different procedures that would attest the certainty and validity of the desired production, after introducing different sets of toxoids and NK cells, the development of the self inducing multiple protein will help in eradicating the symptoms and the effect of FL.It is known that FL is fatal in terms of its effect on the human entire system. So it is important to devise a precise way of handling and dealing with it for them to be able to have an outer perspective of the natural phenomena.Id proteins will act as binders to the solutions that will be used in strengthening NK cells and TSA to promote the development and inhibit the further production of malignant development of tumor cells. By preventing the further growth of it, they would have larger revenue in which they could satisfy the need s and the improvement for having a stronger antigen.Then, natural growth of TSA will be affected by the inducing of soluble protein to target dendritic cells for them to be able to manifest the basic function of fighting foreign toxins that could affect the development of the tumor as a vital implication of the vaccine. The use of different methods in determining the feasibility of inducing the growth and the development of natural antigens that would be sufficient enough to fight the invading tumor cells will be of great use for them to be able t produce more antigens that will prevent the further worsening of the situation.Validating the use f the vaccine as one of the potential sources of defense against the foreign material invading the system would be beneficial if the could handle the needs of having a more systematized and organized level of founding a solution that would focus on the elimination of cell processes that inhibits the growth of malignant tumor like FL that is fa tal to humans.Subjecting enough NK cells to further strengthening process will help them in making the process worthwhile I making a protein Id that would address the situation as founding solution to the antigen development.Goal 5:â€Å"Clinical-grade† production and purification of optimized Id proteins for patient vaccination.After developing the vaccine the process would involve the following:I.   Purifying the Vaccine to be prepared.II.   Final VerificationIII. Mass ProductionIV.   Patient VaccinationPurificationAfter devising the vaccine, the next step is purifying it by eliminating microorganisms that would have effects on the vaccine. By continuously subjecting the vaccine into different microorganism killing environment, they would lessen the potential of having such. Radiating and constantly developing processes will be sufficient in terminating such microorganisms.Final VerificationAfter the purification of the vaccine, a method will be done for them o be abl e to test if the results are really valid by having it tested for final verification. It is important to deal with it because the importance f verifying the vaccine would greatly affects its validity in the medical society. By having it tested trough lab rats or animals that have developed FL tumors; they would be injected with such vaccine for them to see if the previous results will e the same.Mass ProductionAfter the verification process, the next process will involve producing the vaccine enough for human consumption. The proteins that deal with the development of TSA would have a various report on it validity and essentialism for them to be able to have a developed system of introducing vaccines.VaccinationAfter the production and the vaccine is ready to use, it would be given to the patients, as long as it is approved by the medical board, to be sued as vaccine against the development of FL into malignant tumors that endangered the lives of many people. Then, by having the sys tem of production of certain involvement of the NK cells within the hybridoma of dendritic cells, the vaccine will be of much use since it will introduce antigens that will prepare the body for the possible FL development.Since there are certain kinds of toxoids that will be introduced, there will be a harsh reaction at first to the place where it is injected because of the behavior of the toxoids and the T cells of the body. This is a sign that the vaccine is effective and doing a reaction that would strengthen the immune system of the body.DiscussionAfter the development of the vaccine in FL, it is important to understand the need of developing such because of its adverse effect on the development of humans. It endangered the lives of many people without having the prior notification of the said disease. This is a vital step in the clinical world.Considering the existence of the natural antigens present in the environment, by the use of Id proteins that inhibits the growth of tumo r cells; it would be beneficial to mankind if the continuous development will take place. By exploring the kind of the interaction ventured in this kind of process, the elemental composition of the vaccine would be developed to address the needs of the people in having the desired implication of the subject process.The processing of vaccine would include the development of stages in which it would acknowledge the presence of the cells responsible for the development of the disease. In effect, they would have a better understanding on the subject, matter and would increase the possibility of having a curable state.By implicating the notion of having a different technique in addressing the development of the vaccine, the question left for it is how long would it last for them not only to develop vaccine but also to develop a cure that would forever block the negative effects of the disease. By using and ensuring the safety of the user, they would have a proper citation of the needed p lan for them to be able to execute the importance of the vaccine and its use in the modern life.Furthermore, by examining the application of the vaccine in the curing of the disease, we would see the importance of development and use of innovating techniques in determining the possible outcome of the curing of the disease.Finally, the consideration of the process if it fits the standards of the medical consideration despite the fact that there exist different processes that involve much medicinal advancement should take into consideration the impact of the introduction of this vaccine prior to the ethical understanding of the matter.   Since FL can be considered as one of the deadliest disease that one can have, the help of having a vaccine against it is beneficial to the human industry.

Saturday, November 9, 2019

Free Essays on Drivers Ed

Book Report Driver’s Ed by Caroline B. Cooney. This story is about con and facing the consequences for your actions. This book involves the relation ship between 3 friends named Remy Maryland, Morgan Campbell and Nicky Budie. These friends steal signs from this street called cherry road. Nicky stole a â€Å"STOP† sign because she wanted one for her door. About two weeks after a women named Denise Thompson, a mother of a 2 year old boy named Bobby was hit by a garbage truck and died because there was no stop sign. The structure of this story was horizontal. The major events in this story led up to the climax. When these friends got together and stole signs of cherry road they caused the death of an innocent women. These friends now have to learn to face the consequences. An important conflict in this story was man vs. con that these three friends that did something really bad. They were the reason why an innocent woman was killed. They don’t know whether to tell anybody about there secrete or just keep it their secrete. They know if they keep this as a secrete this will haunt them for the rest of their life. Another important conflict in this story was man vs. society. The death of Denise Thompson caused Morgan and Remy to face up to their actions. They both told their parents and driver’s ed teacher. Their drivers ed teacher feels bad for his self because he thinks he failed as a driver’s ed teacher. He thinks his class as a life or death course because in other courses such as English you can pass without the risk of death. The other important conflict in this story was man vs. man. Remy and Morgan both decide to tell Mr. Thompson. They know that he will be hart broken but, they will fell guilty if they don’t tell him. As they both go to the door to explain what happen they start to cry because they see two stocking... Free Essays on Drivers Ed Free Essays on Drivers Ed Book Report Driver’s Ed by Caroline B. Cooney. This story is about con and facing the consequences for your actions. This book involves the relation ship between 3 friends named Remy Maryland, Morgan Campbell and Nicky Budie. These friends steal signs from this street called cherry road. Nicky stole a â€Å"STOP† sign because she wanted one for her door. About two weeks after a women named Denise Thompson, a mother of a 2 year old boy named Bobby was hit by a garbage truck and died because there was no stop sign. The structure of this story was horizontal. The major events in this story led up to the climax. When these friends got together and stole signs of cherry road they caused the death of an innocent women. These friends now have to learn to face the consequences. An important conflict in this story was man vs. con that these three friends that did something really bad. They were the reason why an innocent woman was killed. They don’t know whether to tell anybody about there secrete or just keep it their secrete. They know if they keep this as a secrete this will haunt them for the rest of their life. Another important conflict in this story was man vs. society. The death of Denise Thompson caused Morgan and Remy to face up to their actions. They both told their parents and driver’s ed teacher. Their drivers ed teacher feels bad for his self because he thinks he failed as a driver’s ed teacher. He thinks his class as a life or death course because in other courses such as English you can pass without the risk of death. The other important conflict in this story was man vs. man. Remy and Morgan both decide to tell Mr. Thompson. They know that he will be hart broken but, they will fell guilty if they don’t tell him. As they both go to the door to explain what happen they start to cry because they see two stocking...

Wednesday, November 6, 2019

Sdfdsf Essay Example

Sdfdsf Essay Example Sdfdsf Paper Sdfdsf Paper Business 109 will provide an introduction to the modern business enterprise. We will examine the role of business in a market economy, survey current business trends and the global, financial, and social environment in which businesses exist and operate. Moreover, the course will describe the evolution, formation and management of American and international businesses, and provide a basic understanding of various functional areas of business, including economics, marketing, finance, management, human resources, international operations, and business decision making using information technology. In lieu off final exam, students will be able to get additional experience in the business world through a semester-long final project of building a comprehensive profile of an actual business. The Business Profile project consists of a series of three (3) written research assignments, including corporate background as well as business strategies and practices related to marketing, management, and finance. Students have a choice of either working alone or in a team of two. For extra credit, students may present the profile of the particular business to the entire class at the end of the course. II. LEARNING OBJECTIVES Students will learn to: a. Analyze the relationship and interaction between business enterprises and other institutions b. Develop basic business vocabulary and a familiarity with key business concepts c. Practice and participate in research, business communication, and teamwork activities d. Apply actual business practices in model business situations e. Ill. TEXTBOOK BUSS, 4th Edition, 2011; Clergywomen; ISBN: (Please note you will need to purchase Webster access either from the DVD Bookstore as packaged with the book, or online from within Web). V. GRADING Your grade will be a composite of classroom participation, end-of-chapter quizzes, and a course-long Business Profile project that includes three written assignments. There are total of 1000 points (required) possible for the course: 1. Class Participation @300 points 2 End-of-chapter Quizzes (Best 10 of 12 taken online) 300 @40 points each -400 3. Business Profile Project (3 written assignments) @OHIO points each 300 Total points = 1000 Students will also have the potential to earn a total of 100 extra credit points, 50 of which through clipping business related articles and sharing them with the class inline on the course website, and another 50 of which by presenting the results of your Business Profile project to the whole class at the end of the course. Grade Distribution: 900 1 oho = A (90%) 800-899 = B (80%) 700-799 = c (70%) 600-699 = D (60%) 599 and below = F V. MORE ON QUIZZES, ASSIGNMENTS AND FINAL PROJECT 1. End-of-chapter Quizzes There will be self-administered quizzes for each chapter after you read the chapter in the textbook, go through the Powering Notes and attend lecture. For each quiz, you will be given 60 minutes to complete 20 questions which are true-false or ultimate-choice types. You are given one question at a time and are only allowed one try with the quiz so please do not take the quiz until you are absolutely ready and prepared. Please note that you will not get the results of the quiz until after the quiz deadline. The end-of-chapter quizzes will cover textbook readings, Powering notes, and discussions topics and can be accessed on the Web course site. They will be a combination of multiple-choice and true/false items. Each quiz is worth 40 points and has a deadline that can not be extended. You may take a quiz as early as it becomes available and as late as on the same day before the deadline. No make-up quizzes will be given-No exceptions. You final grade will be based on the best 10 of the 12 quizzes?the two quizzes (including missed quizzes) with the lowest scores will be Please note that there will be NO Final Exam for this class Cheers! Instead, students will participate in a semester-long business profile semester project?see below for details. Warning: Please note that all students are required to abide by the DVD academic honor codes?No cheating of any kind will be tolerated. 2. Written Assignments and Business Profile Project There will be no FINAL EXAM for this class. Instead, students will be able to get additional experience in the business world through a course-long project of building a comprehensive profile of an actual business. The Business Profile project consists of a series of three written research assignments, including corporate background as well as business strategies and practices related to marketing, management, and finance. Students have a choice of either working alone or in a team of two. For extra credit of 50 points, students may present the profile of the particular business to the entire class at the end of the course. Papers should be appropriate pages in length (see Assignment Description on Web), word processed using 12 point type, double spaced. Papers are expected to be proofread and checked for grammar and spelling. Please note that handwritten assignments will NOT be accepted. Assignments are due on the dates listed in the course outline. Please turn in your assignments in class on the dates due and please do NOT upload your assignments online. Late assignments will NOT be accepted. For extra credit, final project presentations can be one using projectors, either via transparency or Microsoft Powering. To help gain valuable teamwork experiences, students are encouraged to work in groups on the course-long business profile project, although individual work will be accepted if student is unable to or do not wish to find another team member. However, group sizes are limited to a maximum of two (2) because as research and experience suggest, the tasks of scheduling team meetings become more difficult as the number of team members increase and team productivity and effectiveness tend to suffer as a result. Remember that all team members will get the same grade for the same project. Having a great team can help reduce individual workload and boost the grades of all team members, but unfortunately the opposite tends to be true as well for a dysfunctional team?so pick your team member(s) carefully! VI. I will keep attendance record regularly and will record any late class arrivals or early departures. According dropped by the instructor. If you are not planning to ever come back to class, be sure to DROP the class yourself with Admissions and Records- it is not my responsibility to o that. Students are also expected to read assigned chapters ahead of scheduled class time and actively participate in class. Please follow the below-listed Reading and Assignment schedule carefully. Your class participation will be an important part (1 [3rd) of your course grade so please take it very seriously if you want to get a good grade in this class.

Monday, November 4, 2019

Emergency Management Essay Example | Topics and Well Written Essays - 500 words

Emergency Management - Essay Example Consistent testing and maintenance of warning systems will help a lot to minimize physical damages and loss of life too. (Emergency Management) Emergency services are organizations which work to ensure the safety of the public, by addressing emergency situations. So it must act to its best in providing information about upcoming events to the public. For this, emergency services must adhere to thoughtful risk communication strategy. It should drive out the fear of public upon certain serious crisis. As well as, make the public believe that the risk existing is low, so that the public could stay with ease. Another important thing is that the emergency services should be in a position to provide accurate as well as quick information. To put it in a nut shell, it should not simply alert and alarm people but educate and inform them about the issue. It should make the public understand, no matter how complex the issue may be. (Emergency Management) The support and cooperation of the public could be well attained only through making them understand the intensity of the situation. If the public is threatened or misguided, then they may not response properly during the crisis. Once gained the hope of the public, we need to do rehearsal of emergency cases. For this the help of emergency response team could be sought. (Lindel, Pratter and Perry) While working within the NIMS, at times necessity may occur such that we need to bring in outside organisations for help. The National Incident Management Systems (NIMS) provides consistent mechanism to effectively prepare for emergency incidents. It can contact other organisations or associations such as public health agencies or EMS organisations in regard with the availability of their training. NIMS integrate the MRC unit and the community’s existing public health and medical service infrastructure. Thus it strengthens the integral component of the emergency response system. (Lindel, Pratter and Perry) Evaluation

Saturday, November 2, 2019

Patient with heart failure Case Study Example | Topics and Well Written Essays - 250 words

Patient with heart failure - Case Study Example rthopnea are caused insufficient flow of blood so that there is no enough oxygen circulating within the body therefore causing a problem of breathing. The symptom of diaphoretic comes about when the body tries to enable the heart muscles pump enough oxygen in blood through the body and this ends up causing profuse perspiration (Molinari & Compare et al., 2006). The priority problems that the patient has based on the nursing assessment done upon admission include, severe dyspnea, a low heartbeat of 132 beats per minute, diaphoresis and a risky blood pressure of 98/70mmhg because they are potentially fatal (Molinari & Compare et al., 2006). ECG is administered before dose 3 and 4 to boost the electrical activity of the heart and increase muscle performance, start IV treatment is used to prevent nausea, vomiting and correct urinary dysfunctions . Remarkably, the nurse should instruct the patient to avoid food items with sodium salt, quit smoking, drinking alcohol, do regular exercise, and lose weight to avoid accumulation of cholesterol around the myocardium. The nurse should teach the patient that digoxin causes a little nausea and vomiting (Molinari & Compare et al.,